No, humanity discovered definitively all germs, not just STI’s – only in 1860 when Pasteur proved germ theory.

Prior to that, some speculated microorganisms were causes of illness, but the vast majority of human history was spent believing ghosts, gods, spirits and other supernatural entities were the causes of illness.

Much quackery existed for the cure of these ailments – chiropractic being one that still survives. Prior to Pasteur, it speculated that misalignment of the spine blocked the energy flow from the brain. It developed its adjustments and other nonsense at that time.  However, as with all irrational beliefs, even though its founding theory was false, it reinvented itself following the emergence of medical science (only in the late 1800’s is it actually medical science) and remains around today, popping, clearing, adjusting, and making money on goobly-gook.

And as if that’s not sad enough, new quackeries have appeared since, such as naturopathic, homeopathic (that one is super hilarious and existed since the middle ages), blood analysis, and other forms of charlatanism continue booming – it is the sad character of this universe that people mourn for those they love and that we all get sick and die. Charlatanism is, however, not a feature we should permit and need to call it out whenever we can, as I do now.